(2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid

(2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid - Names and Identifiers

Name	2-Bromo-5-fluorocinnamic acid
Synonyms	RARECHEM AL BK 0749 2-BROMO-5-FLUOROCINNAMIC ACID 2-Bromo-5-fluorocinnamic acid 3-(2-BroMo-5-fluorophenyl)acrylic acid (E)-3-(2-broMo-5-fluorophenyl)acrylic acid 3-(2-Bromo-5-fluorophenyl)-2-propenoic acid (2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid 2-Propenoic acid, 3-(2-bromo-5-fluorophenyl)- (2E)-3-(2-bromo-5-fluorophenyl)prop-2-enoic acid 2-Propenoic acid, 3-(2-bromo-5-fluorophenyl)-, (2E)-
CAS	202865-70-1
InChI	InChI=1/C9H6BrFO2/c10-8-3-2-7(11)5-6(8)1-4-9(12)13/h1-5H,(H,12,13)/b4-1+

(2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid - Physico-chemical Properties

Molecular Formula	C9H6BrFO2
Molar Mass	245.05
Density	1.685±0.06 g/cm3(Predicted)
Melting Point	188-192°C
Boling Point	332.0±27.0 °C(Predicted)
Flash Point	154.6°C
Vapor Presure	5.97E-05mmHg at 25°C
pKa	4.13±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.624

(2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R25 - Toxic if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
Hazard Note	Irritant

(2E)-3-(2-Bromo-5-fluorophenyl)acrylic acid - Introduction

2-Bromo-5-fluorocinnamic acid is an organic compound with the chemical formula C9H6BrFO2. The following is a description of the nature, use, method and safety information:

Nature:
2-Bromo-5-fluorocinnamic acid is a white crystalline solid, soluble in organic solvents such as ethanol and methylene chloride. It has a special aromatic and acidic taste. The physical and chemical properties depend on the nature of the bromine, fluorine and cinnamic acid groups.

Use:
2-Bromo-5-fluorocinnamic acid is a common intermediate in the field of organic synthesis. It can be used to synthesize other compounds, such as drugs, pesticides, dyes and polymer materials. It can also be used as a derivative of cinnamic acid.

Method:
2-Bromo-5-fluorocinnamic acid can be obtained by reacting 2-bromo-5-fluorobenzoic acid with anhydrous sodium chloride or anhydrous potassium chloride in ether. The reaction is usually carried out at a low temperature to prevent side reactions.

Safety Information:
2-Bromo-5-fluorocinnamic acid is a chemical substance and should be handled with caution. It is irritating and potentially harmful to the skin, eyes and respiratory system. During use and handling, necessary protective measures should be taken, such as wearing protective gloves, glasses and masks, and ensuring a well-ventilated working environment. After accidental contact or inhalation, rinse immediately with water and seek professional medical help. During handling and storage, correct safe operating procedures should be followed and kept away from ignition and combustibles.

Last Update：2024-04-09 15:17:54